Research output per year
Research output per year
Personal profile
Education
1997-1999 Postdoc, Department of Biochemistry & Molecular Biology, Okayama Medical School, Okayama, Japan
1994-1996 Ph.D. in Oral Anatomy, Seoul National University, Seoul, Korea
1988-1990 M.Sc. in Dentistry, Chosun University, Gwang-ju Korea
1981-1987 D.D.S. College of Dentistry, Chosun University, Gwang-ju Korea
1994-1996 Ph.D. in Oral Anatomy, Seoul National University, Seoul, Korea
1988-1990 M.Sc. in Dentistry, Chosun University, Gwang-ju Korea
1981-1987 D.D.S. College of Dentistry, Chosun University, Gwang-ju Korea
Professional experience
1995-2007 Instructor, Assistant professor, Associate professor and Professor, Department of Oral Histology, College of Dentistry, Chosun University. Gwang-ju, Korea
2013- 2014 Associate Dean for Research affairs, School of Dentistry, Seoul National University. Seoul, Korea
2017-2019 Director, Dental Research Institute, Seoul National University
2016- present CEO, HysensBio Co., Ltd.
2007- present Associate professor and Professor, Department of Oral Histology-Developmental Biology, School of Dentistry, Seoul National University. Seoul, Korea
2013- 2014 Associate Dean for Research affairs, School of Dentistry, Seoul National University. Seoul, Korea
2017-2019 Director, Dental Research Institute, Seoul National University
2016- present CEO, HysensBio Co., Ltd.
2007- present Associate professor and Professor, Department of Oral Histology-Developmental Biology, School of Dentistry, Seoul National University. Seoul, Korea
Research Interests
1. Control of odontoblast differentiation and dentin regeneration
2. Periodontium regeneration
3. Maintenance of homeostasis in dental tissue
Key words: Dentin-pulp complex; Periodontal ligament; Regeneration; Homeostasis; Mitochondria;CPNE7
2. Periodontium regeneration
3. Maintenance of homeostasis in dental tissue
Key words: Dentin-pulp complex; Periodontal ligament; Regeneration; Homeostasis; Mitochondria;CPNE7
Major Research Achievements
1. Lee YS, Park YH, Hwang GB, Seo HJ, Ki SH, Bai SF, Roh SM, Park SJ, Lee DS, Lee JH, Seo YM, Shon WJ, Jeon DH, Jang M, Kim SG, Seo BM, Lee G, Park JC. Cpne7 deficiency induces cellular senescence and premature aging of dental pulp. Aging Cell. e14061, 2023
2. Cobo I, Paliwal S, Bodas C, Felipe I, Melià-Alomà J, Torres A, Martínez-Villarreal J, Malumbres M, García F, Millán I, Del Pozo N, Park JC, MacDonald RJ, Muñoz J, Méndez R, Real FX. NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation. Nat Commun. 14(1)3761, 2023
3. Bai, S., Lee, J.-H., Son, C., Lee, D.-S., & Park, J.-C. CPNE7 regenerates periodontal ligament via TAU-mediated alignment and cementum attachment protein-mediated attachment. J Periodont Res, 49(6):609-620, 2022.
4. Park YH, Son C, Seo YM, Lee YS, Har A, Park JC. CPNE7-Induced Autophagy Restores the Physiological Function of Mature Odontoblasts. Front Cell Dev Biol. 26;9:655498, 2021.
5. Park YH, Lee YS, Seo YM, Seo H, Park JS, Bae HS, Park JC. Midkine promotes odontoblast-like differentiation and tertiary dentin formation. J Dent Res. 99(9):1082-1-91, 2020.
2. Cobo I, Paliwal S, Bodas C, Felipe I, Melià-Alomà J, Torres A, Martínez-Villarreal J, Malumbres M, García F, Millán I, Del Pozo N, Park JC, MacDonald RJ, Muñoz J, Méndez R, Real FX. NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation. Nat Commun. 14(1)3761, 2023
3. Bai, S., Lee, J.-H., Son, C., Lee, D.-S., & Park, J.-C. CPNE7 regenerates periodontal ligament via TAU-mediated alignment and cementum attachment protein-mediated attachment. J Periodont Res, 49(6):609-620, 2022.
4. Park YH, Son C, Seo YM, Lee YS, Har A, Park JC. CPNE7-Induced Autophagy Restores the Physiological Function of Mature Odontoblasts. Front Cell Dev Biol. 26;9:655498, 2021.
5. Park YH, Lee YS, Seo YM, Seo H, Park JS, Bae HS, Park JC. Midkine promotes odontoblast-like differentiation and tertiary dentin formation. J Dent Res. 99(9):1082-1-91, 2020.
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Collaborations and top research areas from the last five years
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Evaluation of the Clinical Efficacy of Copine 7-Derived Peptides for Naturally Occurring Periodontitis in Dogs
Kim, S. E., Sung, H., Shin, S., Bae, J., Kim, G., Lee, D. S., Kim, H. W., Seo, J. S., Roh, S. Y., Park, S. J., Son, C., Roh, S. M., Park, J. & Park, J. C., Oct 2025, In: Journal of Clinical Periodontology. 52, 10, p. 1491-1498 8 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Effect of Selcopintide on Periodontal Tissue Regeneration in Chronic One-Wall Intrabony Defect Model
Ko, Y. C., Lee, D. S., Seol, Y. J., Lee, Y. M., Koo, K. T., Park, J. C., Shon, W. J. & Lee, J., Aug 2025, In: Journal of Periodontal Research. 60, 8, p. 835-846 12 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
The impact of selcopintide on periodontal regeneration in a class II furcation defect model: a radiographic and histomorphometric analysis
Jung, J., Lee, J., Lee, S., Koo, K. T., Seol, Y. J., Park, J. C., Park, J., Park, S. J., Son, C., Roh, S. M., Seo, J. S. & Lee, Y. M., May 2025, In: Clinical Oral Investigations. 29, 5, 265.Research output: Contribution to journal › Article › peer-review
Open Access -
Nuclear factor I-C regulates intramembranous bone formation via control of FGF signalling
Lee, J., Park, J. C., Kim, H. J., Bae, H. S. & Lee, D. S., 30 Jan 2025, In: Heliyon. 11, 2, e41789.Research output: Contribution to journal › Article › peer-review
Open Access -
Effect of NAMPT on the proliferation and apoptosis in odontoblast-like MDPC-23 cell
Kang, K. R., Kim, J. S., Seo, J. Y., Lim, H. I., Chun, H. S., Yu, S. K., Kim, H. J., Kim, C. S., Park, J. C. & Kim, D. K., 29 Apr 2024, In: Cellular and Molecular Biology. 70, 3, p. 22-28 7 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations